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Key mammary development regulators are down-regulated in Jarid1b−/− mammary epithelial cells. A and B, validation of genes up-regulated (A) and down-regulated (B) in Jarid1b−/− MECs compared with Jarid1b+/+MECs. C, RT-qPCR analysis of known regulators of mammary gland morphogenesis. D, RT-qPCR analysis of selected estrogen-responsive genes. Error bars represent S.E.
