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Disruption of lipid rafts with MβCD abolishes CysLT1 receptor signaling but not P2Y-evoked responses. A, Ca2+ signals to LTC4 were suppressed following 30 min of pretreatment with MβCD. B, MβCD had no clear effect on ATP-driven Ca2+ signals. Each graph is the average of between 45 and 60 cells from three independent experiments.
