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A–C) Phosphorylation at serine 15, 33, 37 was significantly induced by irradiation (*P<0.05) after 4 hours. The ratio of p53 phosphorylation at Ser 33 and 37 (relative to GAPDH) in KZ-41-treated (10 µM) RECs showed significant reduction (**P<0.05). D) Total p53 protein accumulation revealed significantly reduced levels in KZ-41 treated RECs (**P<0.05).
