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. 2014 Jun 23;9(6):e100210. doi: 10.1371/journal.pone.0100210

Figure 6. Radiation-induced paxillin-dependent proliferative capacity/phenotype.

Figure 6

A) Irradiation-induced REC proliferation was measured after 24 hours using the WST-1 proliferation assay. REC proliferation was enhanced by irradiation and was significantly reduced with treatment of KZ-41 (10 µM) (*P<0.05). B) Paxillin phosphorylation (Y118) was measured 24 hours after irradiation using immunoblotting and showed enhanced levels. Both KZ-41 (10 µM) and p38MAPK inhibitor SB202190 (10 µM) significantly reduced levels of paxillin phosphorylation (*P<0.01, #P<0.05).