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. 2014 Jun 23;9(6):e100295. doi: 10.1371/journal.pone.0100295

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© 2014 Seifert et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Overview of known cancer signaling pathways identified to show largely distinct patterns of overexpressed genes in oligodendrogliomas, astrocytomas and glioblastomas based on predictions of the AR()-HMM(). The overlap of the top-ranking overexpressed genes with the specific signaling pathways is quantified from top 100 to top 600. Grey curves show random expectations with respect to the number of genes in a specific pathway. Robust systematic differences between the different types of gliomas are clearly visible.

Inline graphic — Overview of known cancer signaling pathways identified to show largely distinct patterns of overexpressed genes in oligodendrogliomas, astrocytomas and glioblastomas based on predictions of the AR()-HMM(). The overlap of the top-ranking overexpressed genes with the specific signaling pathways is quantified from top 100 to top 600. Grey curves show random expectations with respect to the number of genes in a specific pathway. Robust systematic differences between the different types of gliomas are clearly visible.