Table 2. Statistical Analysis of Representative HLA Alleles among Patients with Type 1 AIH and Healthy Subjects.
| Allele | Frequency, n (%) | P Value | Pc Value | OR (95% CI) | |
| Patients (2n = 312) | Controls (2n = 402) | ||||
| A*02:01 | 34 (11) | 65 (16) | 0.043 | >0.1 | 0.63 (0.41–0.99) |
| A*24:02 | 108 (35) | 90 (22) | 0.00029 | 0.0053 | 1.84 (1.32–2.55) |
| A*31:01 | 36 (12) | 28 (7) | 0.034 | >0.1 | 1.74 (1.04–2.92) |
| B*15:01 | 19 (6) | 50 (12) | 0.0044 | >0.1 | 0.46 (0.26–0.79) |
| B*39:01 | 11 (4) | 28 (7) | 0.045 | >0.1 | 0.49 (0.24–1.00) |
| B*44:03 | 18 (6) | 41 (10) | 0.033 | >0.1 | 0.54 (0.30–0.96) |
| B*52:01 | 32 (10) | 22 (6) | 0.016 | >0.1 | 1.97 (1.12–3.47) |
| B*54:01 | 40 (13) | 29 (7) | 0.012 | >0.1 | 1.89 (1.14–3.13) |
| C*01:02 | 73 (23) | 58 (14) | 0.0021 | 0.036 | 1.81 (1.24–2.65) |
| C*07:02 | 34 (11) | 69 (17) | 0.018 | >0.1 | 0.59 (0.38–0.92) |
| C*12:02 | 30 (10) | 22 (6) | 0.035 | >0.1 | 1.84 (1.04–3.25) |
| C*14:03 | 17 (5) | 40 (10) | 0.028 | >0.1 | 0.52 (0.29–0.94) |
| DRB1*01:01 | 8 (3) | 24 (6) | 0.029 | >0.1 | 0.41 (0.18–0.94) |
| DRB1*04:03 | 4 (1) | 18 (5) | 0.026 | >0.1 | 0.28 (0.09–0.83) |
| DRB1*04:05 | 95 (30) | 45 (11) | 1.3×10−10 | 4.0×10−9 | 3.47 (2.34–5.14) |
| DRB1*04:06 | 5 (2) | 18 (5) | 0.031 | >0.1 | 0.35 (0.13–0.95) |
| DRB1*13:02 | 13 (4) | 32 (8) | 0.039 | >0.1 | 0.50 (0.26–0.98) |
| DRB1*14:54 | 6 (2) | 20 (5) | 0.031 | >0.1 | 0.37 (0.15–0.94) |
| DRB1*15:01 | 20 (6) | 54 (13) | 0.0023 | 0.068 | 0.44 (0.26–0.75) |
| DQB1*03:02 | 19 (6) | 48 (12) | 0.0078 | >0.1 | 0.48 (0.28–0.83) |
| DQB1*04:01 | 94 (30) | 45 (11) | 2.3×10−10 | 3.7×10−9 | 3.42 (2.31–5.07) |
| DQB1*05:01 | 9 (3) | 31 (8) | 0.0054 | 0.087 | 0.36 (0.17–0.76) |
| DQB1*06:02 | 17 (5) | 53 (13) | 0.0006 | 0.009 | 0.38 (0.22–0.67) |
| DPB1*04:02 | 23 (7) | 52 (13) | 0.016 | >0.1 | 0.54 (0.32–0.90) |
| DPB1*05:01 | 143 (46) | 152 (38) | 0.031 | >0.1 | 1.39 (1.03–1.88) |
Abbreviations: Pc, corrected P; OR, odds ratio; CI, confidence interval.