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. 2014 Jun 23;9(6):e100394. doi: 10.1371/journal.pone.0100394

Figure 7. Effects of mangiferin on the protein expressions and phosphorylation levels of STAT4 and STAT6 in lung tissues of experimental mice.

Figure 7

(A) The levels of p-STAT6 and p-STAT4 in lung tissues were measured by western blot. (B) Bar plot of the average relative density of p-STAT4 and p-STAT6. (C) The levels of GATA3 and T-bet in lung tissues were measured by western blot. (D) Bar plot of the average relative density of GATA3 and T-bet. (E) The expression of STAT6 in lung tissues was detected by immunohistochemistry (magnification 400×), only a representative picture is shown for each group. (a) Normal; (b) Model; (c) Mangiferin 50 mg/kg, (d) Mangiferin 100 mg/kg, (e) Mangiferin 200 mg/kg, (f) Dexamethasone 1.25 mg/kg. Three independent experiments were examined (12 mice in each group of one experiment), Data are expressed as means ± SDs. Compared with model group: * P<0.05; ** P<0.01.