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. 2014 Jun 23;9(6):e100618. doi: 10.1371/journal.pone.0100618

Table 1. Comparisons of Group L and Group H clinical features.

Group L (n = 289) Group H (n = 273) P-value
Age (years) 67.2±14.7 68.1±13.7 0.437
Male gender (n, %) 148 (51.2) 191 (70.0) <0.001
Body mass index (kg/m2) 23.1±4.2 23.3±4.1 0.496
Systolic blood pressure (mmHg) 121.3±17.9 117.8±19.7 0.125
Diastolic blood pressure (mmHg) 72.1±11.2 72.4±12.0 0.868
Heart rate (bpm) 67.5±13.9 71.6±14.8 0.018
Ischemic etiology (n, %) 76 (26.3) 67 (24.5) 0.698
Co-morbidity
Hypertension (n, %) 203 (70.2) 205 (75.1) 0.219
Diabetes (n, %) 91 (31.5) 107 (39.2) 0.064
Dyslipidemia (n, %) 208 (72.0) 200 (73.3) 0.777
Atrial fibrillation (n, %) 92 (31.8) 118 (43.2) 0.007
Anemia (n, %) 120 (41.5) 168 (61.5) <0.001
Medications
ACE inhibitors/ARB (n, %) 217 (75.1) 191 (70.0) 0.186
β-blockers (n, %) 209 (72.3) 218 (79.9) 0.068
Diuretics (n, %) 170 (58.8) 165 (60.4) 0.731
Aldosterone blockers (n, %) 117 (40.5) 114 (41.8) 0.797
Warfarin/anti coagulation (n, %) 144 (49.8) 146 (53.5) 0.399
Laboratory data
White blood cell (×103/µl) 7.30±3.38 7.52±3.35 0.454
Platelet (×103/µl) 18.1±6.5 19.6±7.5 0.019
Hemoglobin (g/dl) 12.7±2.1 11.9±2.7 <0.001
Prothrombin time-international ratio 1.39±0.64 1.50±0.86 0.135
BNP (pg/ml) 236.9 (457) 517.1 (1069) <0.001
Blood urea nitrogen (mg/dl) 24.4±13.3 23.0±12.9 0.239
Creatinine (mg/dl) 0.80±0.18 2.05±1.05 <0.001
eGFR (ml/min/1.73 cm2) 71.0±18.1 40.4±21.9 <0.001
Uric acid (mg/dl) 6.8±2.1 6.5±2.3 0.146
Total protein (g/dl) 7.0±0.8 6.8±0.8 0.014
Albumin (g/dl) 3.7±0.6 3.4±0.6 <0.001
Total bilirubin (mg/dl) 0.8±0.3 1.2±0.7 <0.001
Direct bilirubin (mg/dl) 0.1±0.0 0.2±0.1 <0.001
Aspartate aminotransferase (U/L) 51.6±17.5 52.5±18.7 0.703
Alanine aminotransferase (U/L) 36.5±26.3 43.4±18.6 0.345
Alkaline phosphatase (U/L) 258.1±121.3 297.3±150.8 <0.001
Gamma-glutamyl transferase (U/L) 59.4±32.9 76.8±41.9 0.033
Cholinesterase (U/L) 273.3±82.6 227.0±78.9 <0.001
Sodium (mEq/l) 138.8±4.5 138.9±3.8 0.787
C-reactive protein (mg/dl) 0.35 (1) 0.37 (1) 0.661

ACE, angiotensin-converting enzyme; ARB, angiotensin II receptor blocker; BNP, B-type natriuretic peptide; eGFR, estimated glomerular filtration.

Data are presented as median (interquartile range).