Table 1.

Summary of study outcomes

Metric	OL	Closed loop	P level
Primary outcomes: reduction in hypoglycemia
LBGI	1.12	0.64	0.003
Percentage of time below 3.9 mmol/L (70 mg/dL)	1.25	0.70	>0.1
Number of hypoglycemic episodes/person/session requiring carbohydrate treatment	2.39	1.22	0.021
Grams of carbohydrate/person/session used for treatment of hypoglycemia	39.7	17.6	0.022
Secondary outcomes: glucose control
Percentage of time in the target range of 3.9–10 mmol/L (70–180 mg/dL)	70.7	66.1	>0.1
Percentage of time above 180 mg/dL	28.0	33.1	>0.1
Average BG	8.45 mmol/L (152.1 mg/dL)	8.96 mmol/L (161.3 mg/dL)	0.042
Glucose variability (SD)	2.44 mmol/L (43.9 mg/dL)	2.49 mmol/L (44.9 mg/dL)	>0.1
Total meal carbohydrate content/person/session	272.5 g	266.2 g	>0.1
Total insulin delivered/person/session	62.6 units	59.2 units	>0.1