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. Author manuscript; available in PMC: 2014 Jun 23.
Published in final edited form as: J Pathol. 2012 Jul 18;228(1):77–87. doi: 10.1002/path.4054

Figure 5.

Figure 5

Global serum creatine kinase activity is unaffected by sildenafil treatment. Elevated serum CK (hyperCKaemia) is typically used as a marker of muscle damage. Both vehicle- and sildenafil-treated wild-type animals show characteristically low CK activity. mdx mice exhibited characteristic hyperCKaemia, marked by high levels of serum activity that were unaffected by sildenafil treatment. n = 3 and 4 for vehicle- and sildenafil-treated wild-type mice, respectively. n = 4 and 5 for vehicle- and sildenafil-treated mdx mice, respectively.