Table 1.

Patient characteristics

Pretreatment characteristic (N = 237)	Number (%), median (range)
Males	144 (61)
Age ≥65 years	51 (21)
Age (years)	59 (32-84)
Rai stage III-IV	96 (40)
ALC (K/μL)	75 (1-425)
ALC ≥75 K/μL	119 (50)
Hb (g/dL)	12 (6.9-16.5)
PLT (K/μL)	142 (12-398)
B2M ≥4 mg/L (n = 231)	95 (41)
B2M (mg/L)	3.6 (1.3-14.1)
Unmutated IGHV gene (n = 208)	126 (61)
CD38 ≥30% (n = 225)	97 (43)
CD38 (%)	16 (0.1-99.9)
ZAP70 IHC positive (n= 214)	138 (64)
FISH (n = 222)
del(13q)	73 (33)
negative	47 (21)
+12	39 (18)
del(11q)	47 (21)
del(17p)	16 (7)

ALC, absolute lymphocyte count; Hb, hemoglobin; IHC, immunohistochemistry; PLT, platelet.