Table 4.
HR and hQT stratified according to severe malaria-defining sings and symptoms and selected additional parameters on day 0
| Signs day 0 | No. (%) |
HR (per min) |
hQT (ms, Wernicke) |
||||
|---|---|---|---|---|---|---|---|
| With sign | Without sign | P value | With sign | Without sign | P value | ||
|
Clinical signs | |||||||
| Coma |
48/177 (27) |
144 (±25) |
142 (±28) |
0.688 |
381 (±34) |
381 (±30) |
0.996 |
| Prostration |
155/177 (88) |
142 (±28) |
142 (±23) |
0.983 |
379 (±34) |
396 (±28) |
0.025 |
| Multiple convulsions (per 24 h) |
92/177 (52) |
141 (±26) |
143 (±28) |
0.617 |
381 (±37) |
381 (±30) |
0.967 |
| Respiratory Distress |
22/177 (12) |
152 (±40) |
141 (±25) |
0.069 |
360 (±40) |
384 (±31) |
0.002 |
| Jaundice |
53/177 (30) |
137 (±23) |
144 (±28) |
0.086 |
391 (±34) |
377 (±30) |
0.010 |
| Haemoglubinuria |
36/175 (21) |
136 (±25) |
144 (±28) |
0.147 |
391 (±34) |
379 (±32) |
0.046 |
| Circularly collapse |
14/178 (8) |
147 (±21) |
143 (±25) |
0.506 |
384 (±34) |
381 (±33) |
0.700 |
|
Laboratory signs | |||||||
| Hypoglycaemia |
10/177 (5) |
140 (±51) |
142 (±25) |
0.805 |
375 (±20) |
381 (±34) |
0.595 |
| Metabolic acidosis (BE < −8) |
55/171 (32) |
152 (±32) |
137 (±23) |
<0.001 |
367 (±32) |
388 (±32) |
<0.001 |
| Severe anaemia (Hb < 5 g/dl) |
41/164 (25) |
149 (±35) |
140 (±24) |
0.052 |
383 (±33) |
373 (±33) |
0.089 |
| Hyperparasitaemia |
53/177 (30) |
151 (±21) |
138 (±28) |
0.002 |
374 (±29) |
384 (±35) |
0.086 |
| Hyperlactataemia (>5 mmol/l) |
63/172 (37) |
155 (±28) |
134 (±24) |
<0.001 |
367 (±38) |
389 (±27) |
<0.001 |
| Renal impairment (creatinine >3 mg/dl) |
3/163 (2) |
106 (±31) |
142 (±24) |
0.016 |
411 (±34) |
382 (±32) |
0.128 |
|
Additional parameters | |||||||
| Male gender |
102/177 (58) |
141 (±30) |
144 (±22) |
0.548 |
379 (±33) |
384 (±33) |
0.247 |
| Capillary refill time ≥ 3 s | 17/177 (10) | 135 (±42) | 143 (±25) | 0.255 | 382 (±34) | 380 (±33) | 0.863 |
Values are means (±SD) if not indicated otherwise, unpaired t-test.