Table 4.

Differences between recommendations by change status

	New-replaced recommendations		Not changed recommendations		P a
	(cases, n = 78)		(controls, n = 27)
CGs, n (%)
- Anaemia management in chronic kidney disease	1	(1.3)	-	-	0.036
- Caesarean section	10	(12.8)	1	(3.7)
- Chronic heart failure	4	(5.1)	4	(14.8)
- Chronic obstructive pulmonary disease	-	-	-	-
- Epilepsy	2	(2.6)	5	(18.5)
- Fertility	34	(43.6)	10	(37.0)
- Head injury	3	(3.8)	-	-
- Infection control	24	(30.8)	7	(25.9)
- Lung cancer	-	-	-	-
Time between publication versions, median (range)
- Years	8.8	(4.3-9.0)	8.8	(7.1-9.0)	0.296
CGs topic, n (%)
- Blood and immune system/Urogenital	1	(1.3)	-	-	0.027
- Cardiovascular	4	(5.1)	4	(14.8)
- Central nervous system	2	(2.6)	5	(18.5)
- Gynaecology, pregnancy and birth	44	(56.4)	11	(40.7)
- Injuries, accidents and wounds	3	(3.8)	-	-
- Public health	24	(30.8)	7	(25.9)
- Respiratory	-	-	-	-
Recommendations purpose, n (%)
- Access to services - Referral and approach to care - Service organisation	3	(3.8)	2	(7.4)	0.027
- Diagnostic	7	(9.0)	1	(3.7)
- Monitoring - Follow up	1	(1.3)	5	(18.5)
- Prevention practices	23	(29.5)	7	(25.9)
- Supporting patients and carers	17	(21.8)	2	(7.4)
- Treatment	23	(29.5)	9	(33.3)
- >1 procedure - Others	4	(5.1)	1	(3.7)
Recommendations strength - SIGN, n (%)
- A	25	(32.1)	6	(22.2)	0.296
- B	5	(6.4)	2	(7.4)
- C	11	(14.1)	5	(18.5)
- D	19	(24.4)	7	(25.9)
- GPP	16	(20.5)	6	(22.2)
- Others	2	(2.6)	1	(3.7)

Abbreviations: CG Clinical guidelines, GPP Good practice point.

^aPearson Chi-Square or Mann-Whitney Test, as appropriate.