Table 3-4.

Adjusted incident rate ratio for asthma exacerbations stratified by age

	Ages 18 – 45a	Ages 46 – 64b	Ages 65+c
Prior Conditions	(n = 8,364)	(n = 11,823)	(n = 5,788)
Hypertension	0.97 (0.88–1.06)	0.94 (0.87–1.01)	1.00 (0.91–1.10)
IHD	1.27 (1.01–1.60)d	1.06 (0.94–1.19)	1.15 (1.03–1.27)d
Osteoarthritis	0.77 (0.68–0.87)d	1.04 (0.95–1.13)	0.86 (0.77–0.96)d
Rheumatoid arthritis	0.64 (0.40–1.02)	0.77 (0.59–1.00)	1.18 (0.87–1.60)
Diabetes	1.15 (0.98–1.35)	1.01 (0.92–1.11)	1.00 (0.90–1.11)
Mental disorders	1.44 (1.27–1.63)d	1.28 (1.13–1.44)d	1.39 (1.09–1.78)d
Substance/drug abuse	1.30 (1.11–1.52)d	1.30 (1.11–1.52)d	1.44 (0.71–2.92)
Enlarged prostate	0.86 (0.51–1.45)	0.87 (0.75–1.00)	1.02 (0.92–1.14)
Depression	1.07 (0.97–1.17)	1.09 (1.01–1.19)d	1.07 (0.91–1.26)
Cancer (non-melanoma)	1.08 (0.93–1.26)	0.99 (0.89–1.11)	1.02 (0.92–1.13)
Alcoholism	1.16 (1.00–1.34)	1.29 (1.13–1.48)d	1.15 (0.78–1.70)
HIV	1.05 (0.76–1.44)	1.06 (0.75–1.51)	2.07 (0.65–6.59)
Heart failure	1.36 (0.85–2.17)	1.15 (0.91–1.44)	1.14 (0.97–1.34)
Sleep apnea	1.22 (0.98–1.52)	1.06 (0.90–1.26)	0.87 (0.67–1.14)
GERD	0.87 (0.77–0.99)d	0.84 (0.76–0.93)d	0.83 (0.74–0.94)d
Chronic sinusitis	0.98 (0.85–1.13)	0.89 (0.78–1.01)	1.29 (1.08–1.55)d
Rhinitis	0.77 (0.65–0.93)d	1.15 (1.00–1.33)	0.93 (0.78–1.12)

Definition of Abbreviations: n=number, IHD=Ischemic heart disease, HIV=Human immunodeficiency virus, GERD=Gastroesophageal reflux disease.

^aAdjusted model includes race, prior exacerbations, glucocorticoids, lipid-lowering agents, PPIs, & NSAIDs.

^bAdjusted model includes race, prior exacerbations, primary care visits, glucocorticoids, anti-arrhythmias, lipid-lowering agents, diuretics, & NSAIDs.

^cAdjusted model includes race, prior exacerbations, glucocorticoids, diuretics, and NSAIDs.

^dp<0.05 (In bold).