Fig. 3.

TEM and AFM micrographs of peptides DRV^(9–24), KLL^(45–63), and VLES^(221–239). Evolution of peptide aggregation in water was evaluated by electron and atomic force microscopies on peptides VLES^(221–239) (A–F), DRV^(9–24) (G–L), and KLL^(45–63) (M–R). Incubation times correspond to: 0 h (A, G, M), 24 h (B, H, N), 48 h (C, I, O), 72 h (D, J, P), 92 h (E, K, Q), and 120 days (F, L, R). Arrows (A) show protofibrillar structures. Insets correspond to AFM images of samples used in CD experiments and the scale correspond to 1 µm