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. Author manuscript; available in PMC: 2014 Jun 24.
Published in final edited form as: Thromb Haemost. 2013 Aug 29;110(5):995–1003. doi: 10.1160/TH13-02-0087
What is known on this topic What this paper adds

  • Coagulation traits are highly inter-correlated.

  • A number of common and rare genetic effects on coagulation traits have previously been demonstrated.

  • Replication of a number of previously reported genetic associations

  • Identification of SNPs associated with plasma viscosity and fibrinogen levels

  • Demonstration of pleiotropic effects with SNPs in GCKR and ZNF259-APOA5 suggesting a possible causal role for triglycerides in coagulation.