TABLE 1.
Selected Demographic Characteristics, Sun Exposure, and Tumor Characteristics of Early-Onset BCC Cases and Controls
| Controls, n (%) | Early-Onset BCC Cases, n (%) | |
|---|---|---|
| Age (y) | ||
| <30 | 13 (2.9) | 22 (3.3) |
| 31–40 | 138 (30.5) | 156 (23.7) |
| 41–45 | 123 (27.2) | 191 (29.1) |
| 46–50 | 178 (39.4) | 288 (43.8) |
| Gender | ||
| Men | 184 (40.7) | 251 (38.2) |
| Women | 268 (59.3) | 406 (61.8) |
| Educationa | ||
| Less than college | 128 (28.3) | 142 (21.7) |
| College | 220 (48.7) | 307 (47.0) |
| Graduate or professional school | 104 (23.0) | 204 (31.2) |
| Skin reaction to first hour of sun exposure in summerb | ||
| Tan, or mild burn then tan | 273 (60.5) | 309 (47.1) |
| Painful or blistering sunburn | 178 (39.5) | 347 (52.9) |
| Number of painful sunburnsc | ||
| 0 | 116 (26.8) | 134 (21.9) |
| 1–2 | 95 (21.9) | 89 (14.5) |
| 3–19 | 97 (22.4) | 135 (22.1) |
| ≥20 | 125 (28.9) | 254 (41.5) |
| Hours of sun exposure, warm months, 9 am–5 pmd | ||
| ≤11 026 | 217 (50.0) | 334 (52.8) |
| >11 026 | 217 (50.0) | 298 (47.2) |
| Hours of sun exposure, warm months, 9 am–5 pm in childhoode | ||
| ≤3737 | 221 (50.8) | 336 (52.8) |
| >3737 | 214 (49.2) | 300 (47.2) |
| Proportion of time spent outdoors during nonworking days in childhood | ||
| <1.0 | 44 (10.2) | 81 (12.3) |
| 1.0 | 388 (89.8) | 530 (86.7) |
| Anatomic sitef | ||
| Head or neck | — | 365 (56.9) |
| Trunk | — | 204 (31.8) |
| Upper limb | — | 34 (5.3) |
| Lower limb | — | 30 (4.7) |
| Other sites | — | 8 (1.2) |
| Solar elastosisf | ||
| Absent | — | 4 (1.3) |
| Minimal | — | 57 (17.9) |
| Moderate | — | 97 (30.5) |
| Severe | — | 160 (50.3) |
| Number of BCCsf | ||
| 1 | — | 595 (90.6) |
| >1 | — | 62 (9.4) |
Education missing in 4 cases.
Skin reaction acute sun missing in 1 control, 1 BCC case.
Number of painful sunburns missing in 19 controls and 45 BCC cases.
Number of lifetime hours of sun exposure in warm months missing in 18 controls and 25 BCC cases and categorized based on the median value of the control participants.
Number of lifetime hours of sun exposure in childhood during warm months is missing in 17 controls and 21 BCC cases and categorized based on the median value of the control participants.
Tumors of cases were classified according to their anatomic site of occurrence, the degree of solar elastosis according to the study pathologist's re-review of the diagnostic tumor, and presence of multiple BCC tumors.