TABLE 3.
ORs of Early-Onset BCC and Tanning Lamp Use by Subgroups According to Gender, UV Radiation–Related Factors, Anatomic Site, and Multiplicity
| Subgroup | Tanning Lamp Use | Controls | Early-Onset BCC Cases | OR (95% CI) |
|---|---|---|---|---|
| n (%) | n (%) | |||
| Gender | ||||
| Men | No | 151 (82.0) | 170 (67.7) | Referent |
| Yes | 33 (17.9) | 81 (32.2) | 2.2 (1.4–3.6) | |
| Women | No | 139 (51.8) | 184 (45.3) | Referent |
| Yes | 129 (48.1) | 222 (54.6) | 1.4 (1.0–2.0) | |
| Skin reaction to first hour of sun exposure in summera,b | ||||
| Tan, or mild burn then tan | No | 171 (62.6) | 157 (50.8) | Referent |
| Yes | 102 (37.3) | 152 (49.1) | 1.7 (1.2–2.5) | |
| Painful or blistering sunburn | No | 118 (66.2) | 196 (56.4) | Referent |
| Yes | 60 (33.7) | 151 (43.5) | 1.5 (1.0–2.3) | |
| Lifetime number of painful sunburnsb,c | ||||
| None | No | 82 (70.6) | 76 (56.7) | Referent |
| Yes | 34 (29.3) | 58 (43.2) | 2.5 (1.4–4.5) | |
| 1–2 | No | 61 (64.2) | 44 (49.4) | Referent |
| Yes | 34 (35.7) | 45 (50.5) | 2.0 (1.0–4.0) | |
| 3–19 | No | 58 (61.0) | 80 (64.5) | Referent |
| Yes | 37 (38.9) | 44 (35.4) | 0.8 (0.05–1.5) | |
| ≥20 | No | 74 (59.2) | 125 (49.2) | Referent |
| Yes | 51 (40.8) | 129 (50.7) | 1.6 (1.0–2.5) | |
| Hours of sun exposure, warmer months, 9 am–5 pmb,c | ||||
| ≤11 026 h | No | 134 (61.7) | 169 (50.6) | Referent |
| Yes | 83 (38.2) | 165 (49.4) | 1.6 (1.2–2.4) | |
| >11 026 h | No | 141 (64.9) | 172 (57.7) | Referent |
| Yes | 76 (35.0) | 126 (42.2) | 1.4 (1.0–2.1) | |
| Hours sun exposure, warm months, 9 am–5 pm in childhoodb,c | ||||
| ≤3737 h | No | 139 (62.9) | 182 (54.2) | Referent |
| Yes | 82 (37.1) | 154 (45.8) | 1.5 (1.0–2.2) | |
| >3737 h | No | 136 (63.6) | 159 (53.0) | Referent |
| Yes | 78 (36.5) | 141 (47.0) | 1.7 (1.2–2.5) | |
| Proportion of time spent outdoors during nonworking days in childhoodb,c | ||||
| <1.0 | No | 30 (68.2) | 60 (74.1) | Referent |
| Yes | 14 (31.8) | 21 (25.9) | 0.8 (0.4–1.9) | |
| 1.0 | No | 243 (62.6) | 271 (51.1) | Referent |
| Yes | 145 (37.4) | 259 (48.9) | 1.7 (1.3–2.2) | |
| Solar elastosesc,d | ||||
| Absent, minimal, or moderate | No | 214 (62.9) | 80 (50.6) | Referent |
| Yes | 126 (37.1) | 78 (49.4) | 1.7 (1.1–2.6) | |
| Severe | No | 214 (62.9) | 80 (50.0) | Referent |
| Yes | 126 (37.1) | 80 (50.0) | 2.0 (1.3–3.0) | |
| Anatomic siteb,c | ||||
| Head and neck | No | 290 (64.2) | 209 (57.3) | Referent |
| Yes | 162 (35.9) | 156 (42.7) | 1.4 (1.1–1.9) | |
| All non–head and neck sites | No | 290 (64.2) | 135 (49.3) | Referent |
| Yes | 162 (35.8) | 139 (50.7) | 2.0 (1.5–2.8) | |
| Trunk | No | 290 (64.1) | 97 (47.5) | Referent |
| Yes | 162 (35.8) | 107 (52.4) | 2.1 (1.5–3.1) | |
| Upper limbs | No | 290 (64.1) | 18 (52.9) | Referent |
| Yes | 162 (35.8) | 16 (47.0) | 2.0 (1.0–4.3) | |
| Lower limbs | No | 290 (64.1) | 17 (56.6) | Referent |
| Yes | 162 (35.8) | 13 (43.3) | 1.3 (0.6–2.9) | |
| Number of BCCsb,c | ||||
| 1 BCC | No | 290 (64.1) | 321 (53.9) | Referent |
| Yes | 162 (35.8) | 274 (46.0) | 1.6 (1.2–2.1) | |
| >1 BCC | No | 290 (64.1) | 33 (53.2) | Referent |
| Yes | 162 (35.8) | 29 (46.7) | 1.8 (1.0–3.3) | |
a
Model adjusted for age, gender, and study phase.
b
All 3 phases included.
c
Models adjusted for age, gender, skin reaction to first hour of sun exposure in summer, and study phase.
d
Phases II and III only included.