Table 1.

Clinical characteristic of IBS patients and healthy controls

	Controls (N=495)	IBS (N=422)	p-value
Female: n (%)	331 (66.9%)	331 (78.4%)	<0.001
Age: median (IQR)	36.5 (31)	44 (23)	<0.001
Race/Ethnicity: n (%)			<0.001
Caucasian	247 (49.9%)	303 (71.8%)
Hispanic	59 (11.9%)	25 (5.9%)
Asian	77 (15.6%)	19 (4.5%)
African American	83 (16.8%)	43 (10.2%)
Other/Multiracial	17 (3.4%)	13 (3.1%)
Anxiety Z Score: mean (SEM)	−0.99 (0.94)	0 (0.05)	<0.001
Depression Z Score: mean (SEM)	−0.85 (0.57)	0.99 (0.05)	p<0.001
Bowel Habit Subtype: n (%)			p<0.001
IBS-C		75 (17.8%)
IBS-D		91 (21.6%)
IBS-M		238 (56.4%)
IBS-U		12 (2.8%)