Table 1.
Conditioning |
|
|
---|---|---|
1995–1999 (N=63) | 2000–2004 (N=67) | |
| ||
N (%) | N (%) | |
Reduced intensity | 28 (44%) | 30 (45%) |
Fludarabine / Melphalan | 10 (16%) | 14 (21%) |
Busulfan / Fludarabine | 1 (1%) | 16 (24%) |
Miscellaneous | 17 (27%) | 0 (0%) |
Ablative | 35 (56%) | 37 (55%) |
TBI Containing | 15 (24%) | 2 (3%) |
Busulfan / Cyclophosphamide | 20 (32%) | 12 (18%) |
Busulfan / Fludarabine | 0 (0%) | 23 (34%) |
Stem Cell Source | N (%) | N (%) |
| ||
Matched Related | 42 (67%) | 30 (45%) |
Matched Unrelated | 13 (21%) | 31 (46%) |
Mis-matched Related | 7 (11%) | 3 (5%) |
Mis-matched Unrelated | 0 | 2 (3%) |
Cord Blood | 1 (1%) | 1 (1%) |
Baseline HSCT characteristics. The conditioning regimens and stem cell sources for the 130 allogeneic transplants performed after 1st salvage (S1) are shown above for the time periods 1995–1999 and 2000–2004. Over this time frame more matched unrelated donor transplants were performed. The conditioning regimens used also changed with fewer TBI containing regimens being employed and the majority of transplants being performed with busulfan / fludarabine based conditioning.