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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Horm Behav. 2014 Apr 12;65(5):445–453. doi: 10.1016/j.yhbeh.2014.04.001

Figure 2.

Figure 2

(A) Regularly estrous cycling female GT-tg mice were treated with 7 days of saline (as a control; open bars) or doxycycline (to centrally induce HIV-1 Tat protein; striped bars) and tested in the next proestrous (left bars) or diestrous (right bars) phase of their cycle (n = 20 / group). Anxiety-like behavior was assessed in (B) an open field, (C) an elevated plus maze, and (D) a marble burying task. * indicates significant main effect for doxycycline-treated mice to differ from saline-treated mice. † indicates significant main effect for diestrous mice to differ from proestrous mice, p < 0.05.