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. Author manuscript; available in PMC: 2015 May 6.
Published in final edited form as: Cell Metab. 2014 Apr 17;19(5):872–882. doi: 10.1016/j.cmet.2014.03.010

Figure 5. Dedifferentiated and re-differentiated islet cells are originated from former adult β-cells.

Figure 5

(A,B) (left panels) Representative images of double immunostaining for eGFP (indicating transgene expression in pancreatic β-cells) and insulin (A) or Ngn3 (B) on pancreatic sections from control and both untreated and insulin-treated KATP-GOF mice. Insets show representative cells. (right panels) Percentage immunopositive area of the islet insulin and eGFP (A), or for Ngn3 and eGFP (mean ± s.e.m) (B). Data represent n=5 mice per group, 5 pancreatic sections per mouse.