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Recognition. (A) Diagram showing the key players and processes required for the deposition of the specialized CENP-A-containing nucleosomes at centromeres. (B) (Top) Diagram of the key components of centromeric chromatin. (Bottom) Crystal structures of the H3/H4 tetramer based on data from Davey et al. (2002), CENP-A/H4 tetramer based on data from Tachiwana et al. (2011), and CENP-T/W/S/X heterotetramer based on data from Nishino et al. (2012).
