Table 5.
Voxel-based morphometry results showing regions of significant gray matter intensity decrease that covary with emotional enhancement of memory in bvFTD and AD at p < 0.005, uncorrected for multiple comparisons.
| Regions | BA | Hemisphere | MNI coordinates | Number of voxels | ||
|---|---|---|---|---|---|---|
| X | Y | Z | ||||
| bvFTD | ||||||
| Middle temporal gyrus (posterior division), temporal fusiform cortex, hippocampus, amygdala, orbitofrontal cortex, insula | 20 | Right | 64 | −20 | −16 | 2696 |
| Lateral occipital cortex (superior division) | 39 | Left | −54 | −72 | −24 | 1413 |
| Frontal pole | 46 | Right | 42 | 48 | 18 | 1383 |
| Temporal fusiform cortex (anterior division), parahippocampal gyrus | 20 | Left | −34 | −2 | −38 | 228 |
| Frontal pole | 10 | Left | −40 | 60 | 18 | 172 |
| Precuneus | 30 | Right | 20 | −68 | 12 | 144 |
| Superior frontal gyrus | 8 | Left | −20 | 30 | 40 | 121 |
| AD | ||||||
| Middle frontal gyrus, precentral gyrus | 6 | Left | −26 | 0 | 40 | 352 |
| Planum temporale | 13 | Right | 32 | −28 | 18 | 342 |
| Post−central gyrus | 4 | Left | −36 | −26 | 60 | 193 |
| Temporal fusiform gyrus, parahippocampal gyrus, hippocampus | 20 | Left | −36 | −14 | −26 | 144 |
| Frontal pole | 10 | Left | −28 | 46 | 24 | 122 |
| Planum polare, insular cortex | 21 | Right | 44 | −2 | −10 | 111 |
| Middle temporal gyrus (anterior division) | 21 | Left | −64 | 4 | −14 | 109 |
| Parahippocampal gyrus, hippocampus | 20 | Right | 32 | −10 | −34 | 106 |
| Temporal fusiform gyrus (posterior division) | 37 | Left | −26 | −40 | −22 | 100 |
BA, Brodmann Area.