Table 1.
Characteristics of TB cases in the Netherlands 2005-2012
| |
< 5 years |
5-14 years |
Total 0–14 years |
>14 years |
Total (all ages) |
|||||
|---|---|---|---|---|---|---|---|---|---|---|
| n | % of age group | n | % of age group | n | % of age group | n | % | n | % of age group | |
| Total TB cases (% of total notified) |
154 |
(2%) |
249 |
(3%) |
403 |
(5%) |
7954 |
(95%) |
8357 |
(100%) |
| Male |
82 |
53% |
112 |
45% |
194 |
48% |
4574 |
58% |
4768 |
57% |
| Dutch born, including both parents |
33 |
21% |
69 |
28% |
102 |
25% |
1914 |
24% |
2016 |
24% |
| Dutch born, 2d generation immigrant |
91 |
59% |
63 |
25% |
154 |
38% |
381 |
5% |
535 |
6% |
| Foreign-born |
30 |
19% |
116 |
47% |
146 |
36% |
5,645 |
71% |
5791 |
69% |
|
WHO incidence 2008 country of origin |
|
|
|
|
|
|
|
|
|
|
| <50 |
4 |
13% |
8 |
7% |
12 |
8% |
870 |
15% |
882 |
16% |
|
50-199 |
7 |
23% |
24 |
21% |
31 |
21% |
2673 |
47% |
2704 |
48% |
| >200 |
19 |
63% |
84 |
70% |
68% |
2116 |
37% |
2185 |
39% |
|
| Site of TB disease |
|
|
|
|
|
|
|
|
|
|
| - Primary TB infection |
72 |
47% |
69 |
28% |
141 |
35% |
117 |
1% |
258 |
3% |
| - Pulmonary TB |
51 |
33% |
86 |
35% |
137 |
34% |
4189 |
53% |
4326 |
52% |
| - TB pleuritis |
1 |
1% |
7 |
3% |
8 |
2% |
560 |
7% |
568 |
7% |
| - Other TB of respiratory tract, including intrathoracic lymph nodes |
15 |
10% |
35 |
14% |
50 |
12% |
896 |
11% |
946 |
11% |
| - TB of peripheral lymph nodes |
7 |
5% |
32 |
13% |
39 |
10% |
1260 |
16% |
1299 |
16% |
| - miliary TB |
3 |
2% |
7 |
3% |
10 |
2% |
203 |
3% |
213 |
3% |
| - TB meningitis |
3 |
2% |
4 |
2% |
7 |
2% |
177 |
2% |
184 |
2% |
| - Bone and joint TB |
0 |
0% |
5 |
2% |
5 |
1% |
341 |
4% |
346 |
4% |
| - TB of other organ tracts |
2 |
1% |
10 |
4% |
12 |
3% |
732 |
9% |
744 |
9% |
| Culture positive |
36 |
23% |
93 |
37% |
129 |
32% |
5,867 |
74% |
4611 |
55% |
| History of TB contact |
105 |
68% |
132 |
53% |
237 |
59% |
606 |
8% |
843 |
10% |
| Hiv-co-infection |
1 |
1% |
2 |
1% |
|
1% |
326 |
4% |
329 |
4% |
| Diagnosis by MPHS |
104 |
68% |
140 |
56% |
244 |
61% |
1509 |
19% |
1753 |
21% |
| Active case finding |
|
|
|
|
|
|
|
|
|
|
| - Contact investigation |
101 |
66% |
128 |
51% |
229 |
57% |
390 |
5% |
619 |
7% |
| - Screening immigrants |
11 |
7% |
18 |
7% |
29 |
7% |
856 |
11% |
885 |
11% |
| Hospital admission >1 week |
23 |
15% |
41 |
16% |
64 |
16% |
2652 |
33% |
2716 |
32% |
| Daily observed treatment |
88 |
57% |
116 |
47% |
204 |
51% |
2114 |
27% |
2318 |
28% |
| Adverse events* |
4 |
3% |
12 |
5% |
16 |
4% |
1022 |
13% |
1038 |
12% |
| Treatment Outcome |
135 |
|
218 |
|
353 |
|
7046 |
|
7399 |
|
| - Success |
124 |
92% |
207 |
95% |
331 |
94% |
6070 |
86% |
6401 |
87% |
| - Defaulted |
5 |
4% |
3 |
1% |
8 |
2% |
255 |
4% |
263 |
4% |
| - Death caused by TB |
2 |
1% |
1 |
0% |
3 |
1% |
135 |
2% |
138 |
2% |
| - Death caused by other cause |
1 |
1% |
0 |
0% |
1 |
0.3% |
271 |
4% |
272 |
4% |
| - Transfer out/unknown | 3 | 2% | 7 | 3% | 10 | 3% | 315 | 4% | 325 | 4% |
Definition of abbreviations: NL Netherlands, CI contact investigation, MPHS Municipal Public Health Service, HIV human immunodeficiency virus, TB tuberculosis, BCG Bacillus Calmette-Guérin.
*Adverse events- defined as events demanding an interruption or change of the treatment regimen.