Table 2.

Effect of GMP human SAP on cytokine production/release by human peripheral blood mononuclear cells in vitro.

Experiment	Protein	Cytokine responses
		IL-1β (pg/mL)	IL-10 (pg/mL)
4	Medium only control	6 ± 3	24 ± 17
	SAP (1.0, 10.0, 100 μg/mL)	24 ± 4, 24 ± 2, 5 ± 5	34 ± 20, 31 ± 18, 43 ± 26
	ET (0.03, 0.06, 0.075 EU/mL)	172 ± 72, 739 ± 316, 997 ± 335	29 ± 26, 78 ± 47, 112 ± 41
	ET spike recovery (%) for SAP (100 μg/mL) + ET (0.075 EU/mL):
		107 ± 13%	182 ± 110%

Values are mean ± SEM; n = 4 donors of PBMC; ET, endotoxin.