Skip to main content
. Author manuscript; available in PMC: 2014 Jun 24.
Published in final edited form as: ACS Chem Biol. 2014 Jan 6;9(3):722–730. doi: 10.1021/cb4008953

Figure 2.

Figure 2

The effect of dimeric quinine compounds on PfCRTCQR-mediated transport of CQ in X. laevis oocytes. [3H]CQ uptake into oocytes expressing Dd2 PfCRTCQR (black bars) or D10 PfCRTCQS (white bars) in the presence of unlabeled dimeric compounds (100 µM), quinine (100 or 200 µM), or verapamil (100 µM). Uptake is shown as the mean + SEM from n = 4 separate experiments, within which measurements were made from 10 oocytes per treatment.