Skip to main content
. Author manuscript; available in PMC: 2014 Jun 24.
Published in final edited form as: ACS Chem Biol. 2014 Jan 6;9(3):722–730. doi: 10.1021/cb4008953

Figure 4.

Figure 4

Concanamycin A-induced digestive vacuole (DV) alkalinization in pfcrt transfectant lines. The rate of concanamycin A-induced DV alkalinization in the pfcrt transfectant lines C2GC03 (CQS; white bars), C4Dd2 (CQR; black bars), and C67G8 (CQR; gray bars) was measured in the absence (solvent control) and presence of the compounds indicated. Compounds were added to the parasite suspensions 4 min before the addition of concanamycin A (100 nM). The data are averaged from three independent experiments and shown + SEM: (a) 1, 6, and quinine were all added at a final concentration of 1 µM; (b) CQ was added at a concentration of 2.5 µM in the presence or absence of 1 (1 µM) and 6 (1 µM).