Table IV.

Estimated rate constants for the unified GPx kinetic model for different experimental data sets.

Carsol et al. [39]
				Value			Value
Parameter	Value	Sensitivity	Parameter	pH = 7.0	pH = 7.7	Parameter	pH = 7	pH = 7.7
k1f (M−1 s−1)	2.2 × 105	0.53	Vf (s−1)a	4.46	4.46	Φ0(s)a	0.22	0.22
k1r (s−1)	9.8 × 107	0.41	KmA (M)	0.1 (2.5)	2.5	Φ1 (M. s)a	4.4 × 10−6	4.4 × 10−6
k2f (M−1 s−1)	1.3 × 108	0.41	KmA1 (M)	35 × 10−6	832 × 10−6	Φ2 (M. s)	1.5 × 10−3	3.2 × 10−4
k2r (s−1)	3.6 × 103	0.17	KmA2 (M)a	20 × 10−6	20 × 10−6	Φ12 (M2. s)	5.4 × 10−8	2.7 × 10−7
k3f (M−1 s−1)	4 × 104	0.42	KmB1 (M)	0.45 × 10−6	2.27 × 10−6	Φ22 (M2. s)	6.9 × 10−10	7.3 × 10−10
k3r (s−1)b	4.0 × 10−33	N/A	KmB2 (M)	6.8 × 10−3	1.45 × 10−3	Φ122 (M3. s)	7.4 × 10−11	1.8 × 10−9
k4f (s−1)	4.47	0.32	KiB1 (M)	1.3 × 10−3	6.9 × 10−3
k4r (M−1 s−1)	4.1 × 102	0.32	KiB2 (M)	12 × 10−3	60 × 10−3
KH (M)	1.5 × 10−9	N/A	KmP(M)	10 × 10−3	10 × 10−3
Keq (M−2)	9.0 × 1036	N/A	Vr (s−1)	0	0

N/A: Not applicable as they are fixed parameters.

^aIndependent of pH.

^bParameter was calculated based on the thermodynamic constraint.