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. Author manuscript; available in PMC: 2014 Jun 24.
Published in final edited form as: J Clin Psychiatry. 2011 Sep;72(9):1190–1196. doi: 10.4088/JCP.10087co1c

Table 2.

Brain Imaging and CSF Biomarkers That Have Shown Promise in Improving Confidence in the Differential Diagnosis of MCI Due to AD and Dementia Due to AD

MRI measurements of atrophy in the hippocampus and other AD-affected brain regions
PET measurements of glucose hypometabolism in AD-affected brain regions
PET measurements of fibrillar Aβ deposition
CSF measurements of low Aβ42, alone or in combination with high total tau and/or phospho-tau levels

Abbreviations: Aβ = amyloid-beta, AD = Alzheimer’s disease, CSF = cerebrospinal fluid, MCI = mild cognitive impairment, PET = positron emission tomography.