TABLE 1.
Demographic characteristicsa
| Parameter | Value for the indicated gestational age (wk) and PNA (days) |
Total | |||
|---|---|---|---|---|---|
| ≤34 |
>34 |
||||
| ≤7 | 8–28 | ≤7 | 8–28 | ||
| Group no. | 1 | 2 | 3 | 4 | |
| n | 21 | 7 | 27 | 18 | 73 |
| Postnatal age (days) at day of first plasma PK sample | |||||
| Mean (SD) | 2.6 (2.3) | 15.4 (4.0) | 2.9 (2.6) | 13.4 (5.4) | 6.6 (6.4) |
| Median (minimum, maximum) | 1.0 (0.0, 7.0) | 16.0 (9.0, 21.0) | 2.0 (0.0, 7.0) | 12.5 (8.0, 25.0) | 5.0 (0.0, 25.0) |
| Gestational age (wk) | |||||
| Mean (SD) | 30.3 (3.4) | 26.9 (2.5) | 38.2 (2.0) | 38.4 (1.8) | 34.9 (5.0) |
| Median (minimum, maximum) | 32.3 (24.0, 34.0) | 26.1 (25.0, 32.0) | 38.0 (34.0, 41.0) | 38.8 (35.0, 41.0) | 36.1 (24.0, 41.0) |
| No. (%) male | 9 (43) | 3 (43) | 18 (67) | 8 (44) | 38 (52) |
| Ethnicity, no. (%) | |||||
| Hispanic or Latino | 3 (14) | 1 (14) | 6 (22) | 3 (16) | 13 (18) |
| Not Hispanic or Latino | 18 (86) | 5 (71) | 19 (70) | 14 (78) | 56 (77) |
| Not reported | 0 | 1 (14) | 2 (7) | 1 (6) | 4 (6) |
| Race, no. (%) | |||||
| Black | 4 (19) | 3 (43) | 3 (11) | 2 (11) | 12 (16) |
| White | 16 (76) | 3 (43) | 23 (85) | 14 (78) | 56 (77) |
| Not reported | 0 | 0 | 0 | 1 (6) | 1 (1) |
| Other | 1 (5) | 1 (14) | 0 | 1 (6) | 3 (4) |
a
PK, pharmacokinetic; PNA, postnatal age.