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Structure, anti-HIV activity, and ADME properties of compounds 16a to 16m
Values are expressed as mean ± SD. The experiments were repeated three times in triplicate.
PAMPA calculated as Papp × 10−6 cm/s, see Materials and Methods for details; %MR, percent membrane retention.
LogS = log mol · liter−1.
Expressed as percentage of unmodified parent.
