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. 2014 Jun;58(6):3475–3480. doi: 10.1128/AAC.02426-14

TABLE 1.

Drug susceptibility patterns of 171 clinical M. tuberculosis isolates

Susceptibility or resistance category or drug(s) Total patients (n = 171)
New patients (n = 97)
Previously treated patients (n = 74)
No. % (95% CI) No. % (95% CI) No. % (95% CI)
Overall susceptibility to first-line drugs 101 59.1 (52.0–66.4) 78 80.4 (72.5–88.3) 23 31.1 (20.5–41.6)
Overall first-line drug resistance 70 40.9 (33.6–48.3) 19 19.6 (11.7–27.5) 51 68.9 (58.4–79.5)
INH 61 35.7 (28.5–42.9) 13 13.4 (6.6–20.2) 48 64.9 (54.0–75.7)
RIF 46 26.9 (20.3–33.6) 7 7.2 (2.1–12.4) 39 52.7 (41.3–64.1)
SM 35 20.5 (14.4–26.5) 13 13.4 (6.6–20.2) 22 29.7 (19.3–40.1)
EMB 17 9.9 (5.5–14.4) 2 2.1a 15 20.3 (11.1–29.4)
PZA 26 15.2 (9.8–20.6) 3 3.1a 23 31.1 (20.5–41.6)
Overall MDR 43 25.2 (18.6–31.7) 6 6.2 (1.4–11.0) 37 50.0 (38.6–61.4)
INH + RIF 10 5.9 (2.3–9.4) 1 1.0a 9 12.1 (4.7–19.6)
INH + RIF + SM 7 4.1 (1.1–7.1) 2 2.1a 5 6.8a
INH + RIF + EMB 1 0.6a 0 0 1 1.4a
INH + RIF + PZA 7 4.1 (1.1–7.1) 0 0 7 9.5 (2.8–16.1)
INH + RIF + SM + EMB 3 1.8a 0 0 3 4.1a
INH + RIF + SM + PZA 4 2.3a 1 1.0a 3 4.1a
INH + RIF + EMB + PZA 4 2.3a 0 0 4 2.3a
INH + RIF + SM + EMB + PZA 7 4.1 (1.1–7.1) 2 2.1a 5 5.4a
Susceptibility to all second-line drugs 152 88.9 (84.2–93.6) 95 98.0a 57 77.0 (67.4–86.6)
Overall second-line drug resistance 19 11.1 (6.4–15.8) 2 2.1a 17 22.9 (13.4–32.6)
CAP 4 2.3a 0 0 4 5.4a
KAN 3 1.8a 0 0 3 4.1a
AKM 2 1.2a 0 0 2 2.7a
OFX 18 10.5 (5.9–15.1) 2 2.1a 16 21.6 (12.2–31.0)
Overall pre-XDR 15 8.7 (4.5–13.0) 1 1.0a 14 14.9 (6.8–23.0)
CAP 4 2.3a 0 0 4 1.4a
KAN 3 1.8a 0 0 3 1.4a
AKM 2 1.2a 0 0 2 0
OFX 14 8.2 (4.1–12.3) 1 1.0a 13 13.5 (5.7–21.3)
Overall XDR 3 1.8a 0 0 3 4.1a
CAP + OFX 1 0.6a 0 0 1 1.4a
CAP + KAN + AKM + OFX 2 1.2a 0 0 2 2.7a
a

95% CI was not determined.