TABLE 1.
Susceptibility or resistance category or drug(s) | Total patients (n = 171) |
New patients (n = 97) |
Previously treated patients (n = 74) |
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---|---|---|---|---|---|---|
No. | % (95% CI) | No. | % (95% CI) | No. | % (95% CI) | |
Overall susceptibility to first-line drugs | 101 | 59.1 (52.0–66.4) | 78 | 80.4 (72.5–88.3) | 23 | 31.1 (20.5–41.6) |
Overall first-line drug resistance | 70 | 40.9 (33.6–48.3) | 19 | 19.6 (11.7–27.5) | 51 | 68.9 (58.4–79.5) |
INH | 61 | 35.7 (28.5–42.9) | 13 | 13.4 (6.6–20.2) | 48 | 64.9 (54.0–75.7) |
RIF | 46 | 26.9 (20.3–33.6) | 7 | 7.2 (2.1–12.4) | 39 | 52.7 (41.3–64.1) |
SM | 35 | 20.5 (14.4–26.5) | 13 | 13.4 (6.6–20.2) | 22 | 29.7 (19.3–40.1) |
EMB | 17 | 9.9 (5.5–14.4) | 2 | 2.1a | 15 | 20.3 (11.1–29.4) |
PZA | 26 | 15.2 (9.8–20.6) | 3 | 3.1a | 23 | 31.1 (20.5–41.6) |
Overall MDR | 43 | 25.2 (18.6–31.7) | 6 | 6.2 (1.4–11.0) | 37 | 50.0 (38.6–61.4) |
INH + RIF | 10 | 5.9 (2.3–9.4) | 1 | 1.0a | 9 | 12.1 (4.7–19.6) |
INH + RIF + SM | 7 | 4.1 (1.1–7.1) | 2 | 2.1a | 5 | 6.8a |
INH + RIF + EMB | 1 | 0.6a | 0 | 0 | 1 | 1.4a |
INH + RIF + PZA | 7 | 4.1 (1.1–7.1) | 0 | 0 | 7 | 9.5 (2.8–16.1) |
INH + RIF + SM + EMB | 3 | 1.8a | 0 | 0 | 3 | 4.1a |
INH + RIF + SM + PZA | 4 | 2.3a | 1 | 1.0a | 3 | 4.1a |
INH + RIF + EMB + PZA | 4 | 2.3a | 0 | 0 | 4 | 2.3a |
INH + RIF + SM + EMB + PZA | 7 | 4.1 (1.1–7.1) | 2 | 2.1a | 5 | 5.4a |
Susceptibility to all second-line drugs | 152 | 88.9 (84.2–93.6) | 95 | 98.0a | 57 | 77.0 (67.4–86.6) |
Overall second-line drug resistance | 19 | 11.1 (6.4–15.8) | 2 | 2.1a | 17 | 22.9 (13.4–32.6) |
CAP | 4 | 2.3a | 0 | 0 | 4 | 5.4a |
KAN | 3 | 1.8a | 0 | 0 | 3 | 4.1a |
AKM | 2 | 1.2a | 0 | 0 | 2 | 2.7a |
OFX | 18 | 10.5 (5.9–15.1) | 2 | 2.1a | 16 | 21.6 (12.2–31.0) |
Overall pre-XDR | 15 | 8.7 (4.5–13.0) | 1 | 1.0a | 14 | 14.9 (6.8–23.0) |
CAP | 4 | 2.3a | 0 | 0 | 4 | 1.4a |
KAN | 3 | 1.8a | 0 | 0 | 3 | 1.4a |
AKM | 2 | 1.2a | 0 | 0 | 2 | 0 |
OFX | 14 | 8.2 (4.1–12.3) | 1 | 1.0a | 13 | 13.5 (5.7–21.3) |
Overall XDR | 3 | 1.8a | 0 | 0 | 3 | 4.1a |
CAP + OFX | 1 | 0.6a | 0 | 0 | 1 | 1.4a |
CAP + KAN + AKM + OFX | 2 | 1.2a | 0 | 0 | 2 | 2.7a |
95% CI was not determined.