TABLE 1.

Final parameter estimates and 90% CIs

Parameter	Estimate	90% CI
Fixed effects
WBA0 (Δlog/d)	0.182	0.154–0.209
Imax (Δlog/d)	0.597	0.559–0.636
IC50480 (ng/ml)	70.4	56.0–84.9
IC50603 (ng/ml)	1,200	839–2,960
γ480	2.25	1.7–3.2
γ603	(0.94)a
Random effects
WBA0 (%)	27.4	19.4–35.2
Sigmab	0.096	0.075–0.114

^aThe initial estimate for γ₆₀₃ (0.94) could not be distinguished from 1 and was omitted from the final model.

^bSigma, residual error.