TABLE 4.

Linear regression of data for individual patients with different numbers of observations

Patient	1 observation		2 observations		3 observations		6 observations
	r2	Predicted piperacillin dose (g) [% of delivered dose]	r2	Predicted piperacillin dose (g) [% of delivered dose]	r2	Predicted piperacillin dose (g) [% of delivered dose]	r2	Predicted piperacillin dose (g) [% of delivered dose]
1	0.861	2.68 [−33.0]	0.918	5.22 [30.5]	0.972	4.87 [21.7]	0.940	4.97 [24.3]
2	0.928	1.76 [−55.9]	0.947	1.15 [−71.3]	0.897	1.71 [−57.2]	0.897	1.67 [−58.2]
3	0.976	9.49 [137.3]	0.981	8.72 [118.1]	0.883	11.64 [191.0]	0.959	17.65 [341.2]
4	0.925	3.10 [−22.4]	0.919	3.05 [−23.9]	0.890	3.53 [−11.8]	0.833	3.42 [−14.5]
5	0.987	4.81 [20.3]	0.987	4.33 [8.3]	0.979	5.05 [26.1]	0.892	5.62 [40.5]
6	0.963	3.04 [−23.9]	0.920	3.83 [−4.3]	0.970	3.76 [−5.9]	0.938	5.05 [26.2]
7	0.967	1.85 [−53.8]	0.959	3.10 [−22.4]	0.960	3.32 [−17.0]	0.967	3.08 [−23.0]
8	0.905	1.89 [−52.6]	0.893	2.76 [−31.0]	0.893	2.54 [−36.4]	0.859	2.71 [−32.3]
Mean		3.58 [−10.5]		4.02 [0.5]		4.55 [13.8]		5.52 [38.0]
Median		2.86 [−28.5]		3.47 [−13.4]		3.65 [−8.8]		4.20 [4.9]