TABLE 1.
Cohort | No. of animals | Drugsa | ART classes | Treatment initiation (wk) |
---|---|---|---|---|
3-drug | 8 | (−)-FTC, TFV, EFV | 2 NRTI, 1 NNRTI | 6 |
4-drug | 4 | (−)-FTC, TFV, EFV, L-812 | 2 NRTI, 1 NNRTI, 1 INI | 6 |
5-drug | 7 | (−)-FTC, TFV, EFV, AZT, DAPD | 4 NRTI, 1 NNRTI | 8 |
EFV, L-812, and DAPD were compounded into drug paste (1 dose/ml) from bulk powder using sucrose solution (63%).