TABLE 5.
Association of M. tuberculosis strain lineage with resistance to any of the anti-TB drugs in Kampala
| Lineage | Total no. of isolates | No. (%) of isolates resistant to any anti-TB drug | Crude odds ratio (95% CI) | Adjusted odds ratio (95% CI)a | P value |
|---|---|---|---|---|---|
| T2/T2-Uganda | 227 | 26 (11.5) | Reference | Reference | |
| CAS | 49 | 15 (30.6) | 3.4 (1.6–7.1) | 2.9 (1.4–6.3) | 0.006 |
| LAM | 32 | 11 (34.4) | 4.1 (1.7–9.3) | 5.0 (2.1–11.9) | <0.001 |
| T1 | 36 | 8 (22.2) | 2.2 (0.9–5.3) | 2.4 (1.0–6.2) | 0.070 |
| Unknown | 107 | 9 (8.41) | 0.7 (0.3–1.6) | 0.7 (0.3–1.6) | 0.450 |
| Otherb | 46 | 6 (13.0) | 1.2 (0.4–3.0) | 1.1 (0.4–3.0) | 0.820 |
a
Based on multivariable logistic regression model, including age, sex, treatment history, history of imprisonment, and history of health care work.
b
Includes Haarlem, EAI, MANU, S, undesignated, T2T3, T3_Eth, and Beijing.