TABLE 3.
Percentage of daptomycin penetration into bone (thighbone and shinbone) and synovial fluid sampled in a mean time of 7.3 h after the perfusion of 8 mg/kg of daptomycin. The results are expressed by the mean, standard deviation (SD), median, first quartile (Q1), third quartile (Q3); min and max
| Measurementa | Penetration (%) in: |
|||
|---|---|---|---|---|
| Thighbone (n = 16) | Shinbone (n = 10) | Bone (n = 26) | Synovial fluid (n = 13) | |
| Mean | 9.5 | 8.2 | 14.1 | 53.9 |
| SD | 5.0 | 4.7 | 11.9 | 15.9 |
| Median | 9.9 | 8.0 | 11.1 | 54.2 |
| Minimum | 2.9 | 3.1 | 3.0 | 32.8 |
| Q1 | 6.5 | 4.4 | 6.6 | 38.5 |
| Q3 | 11.7 | 10.5 | 17.3 | 60.3 |
| Maximum | 20.2 | 18.1 | 50.4 | 86.6 |
a
Q1 and Q3, first and third quartiles, respectively.