TABLE 5.
Rabbit efficacy study survival results
| AVP-21D9 dose (mg/kg) | All animals |
Animals bacteremic prior to treatment |
||
|---|---|---|---|---|
| No. survived/no. dosed | Survival proportion (95% confidence interval) | No. survived/no. dosed | Survival proportion (95% confidence interval) | |
| 20 | 9/12 | 0.75 (0.43, 0.95) | 6/9 | 0.67 (0.30, 0.93) |
| 10 | 13/14 | 0.93 (0.66, 1.00) | 10/11 | 0.91 (0.59, 1.00) |
| 5 | 13/14 | 0.93 (0.66, 1.00) | 12/13 | 0.92 (0.64, 1.00) |
| 1 | 8/14 | 0.57 (0.29, 0.82) | 3/9 | 0.33 (0.07, 0.70) |
| 0 (saline) | 0/8 | 0.00 (0.00, 0.37) | 0/6 | 0.00 (0.00, 0.46) |