TABLE 1.

Cumulative drug amount permeated after a single application of efinaconazole 10% solution, ciclopirox 8% nail lacquer, and amorolfine 5% nail lacquer to human nails^a

Time (day)	Cumulative amt permeated (μg/cm2) for:
	Efinaconazole	Ciclopirox	Amorolfine
1	0.401 ± 0.672	NCb	NC
2	0.742 ± 1.242	NC	NC
3	1.29 ± 1.91	NC	NC
4	1.59 ± 2.37	NC	NC
5	2.16 ± 3.11	NC	NC
6	2.57 ± 3.49	0.0998 ± 0.2445	NC
7	2.94 ± 3.91	0.326 ± 0.590	NC
8	3.45 ± 4.46	0.535 ± 0.908	NC
9	3.98 ± 5.20	0.895 ± 1.495	NC
10	4.49 ± 5.70	1.32 ± 2.18	NC
11	4.84 ± 6.12	2.03 ± 3.32	NC
12	5.42 ± 6.97	2.82 ± 4.34	NC
13	5.90 ± 7.39	3.56 ± 5.43	NC
14	6.53 ± 8.15	4.57 ± 6.89	NC

^aData represent mean ± SD (n = 6).

^bNC, not calculated because drug concentration in the receptor phase was below the lower limit of quantification (<1 ng/ml) in all samples.