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Effect of SNX-2112 on E. histolytica morphology. Trophozoites were treated with 3 μM SNX-2112 for 48 h. (A) E. histolytica trophozoites treated with 0.5% DMSO. Arrow indicates live trophozoite. Magnification, ×10. (B) E. histolytica trophozoites treated with 3 μM SNX-2112. Treatment caused complete lysis of trophozoites (arrow). Magnification, ×10. Trophozoites were imaged under phase-contrast microscope.
