TABLE 1.
Summary of the tyrocidines and analogues used in this study
| Peptide | Abbreviation | Sequenceb | Monoisotopic Mr (theoretical Mr)c |
|---|---|---|---|
| Tyrocidine A | TrcA | cyclo-(VOLfPFfNQY) | 1,269.6515 (1,269.6546) |
| Tyrocidine B | TrcB | cyclo-(VOLfPWfNQY) | 1,308.6610 (1,308.6655) |
| Tyrocidine C | TrcC | cyclo-(VOLfPWwNQY) | 1,347.6713 (1,347.6764) |
| Phenycidine Aa | PhcA | cyclo-(VOLfPFfNQF) | 1,253.6625 (1,253.6597) |
| Tryptocidine C | TpcC | cyclo-(VOLfPWwNQW) | 1,370.6866 (1,370.6924) |
| Gramicidin S | GS | cyclo-(VOLfPVOLfP) | 1,140.7067 (1,140.7059) |
a
Named by Vosloo et al. (34).
b
Conventional one-letter abbreviations are used for amino acids, except that O was used for ornithine. Lowercase one-letter abbreviations indicate d-amino acid residues. The sequence data obtained from Tang et al. (29) and the identities were confirmed by our group (34, 35).
c
Detected monoisotopic Mr of peptides determined from purified peptides using high-resolution time of flight-electrospray mass spectrometry (TOF-ESMS) (refer to Table S1 in the supplemental material).