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CFZ was effective in immunocompromised GKO mice. Gamma interferon gene-disrupted mice were treated for 9 days with 20 mg/kg CFZ beginning on day 13 postinfection. CFZ reduced bacterial loads in the lungs (A) by 3.1 log10 CFU and in the spleens (B) by 3.95 log10 CFU compared to results for untreated controls. Data represent mean log10 CFU counts ± SEM; detection limit = 50 CFU. *, P < 0.001.
