FIG 3.

Uptake of VGP-106 in Leishmania lines. (A) Kinetics of VGP-106 uptake at 28°C in promastigotes of L. donovani and L. major lines. Samples were taken at different time points, and VGP-106 uptake was determined fluorimetrically as described in Materials and Methods. Data are representative of three independent experiments (means ± standard deviations [SD]). (B) Differences in VGP-106 accumulation in promastigotes of L. donovani and L. major at 28°C and 4°C. Data are representative of three independent experiments (means ± SD).