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Activity (EC50s) and selective index (SI) of 18SAB075 against intracellular forms of T. cruzi (Y strain) after treatment for 48 h at 37°C. (A) T. cruzi-infected cardiac cells incubated with vehicle. (B) T. cruzi-infected cardiac cells incubated with 32 μM 18SAB075. The arrows point to intracellular parasites. Infection index, host cell infection × number of parasites/infected host cell, as reported in Batista et al. (15).
