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In vivo effect of 18SAB075 on T. cruzi infection using male Swiss mice inoculated with 104 bloodstream trypomastigotes (Y strain). The activities of 5, 10, and 20 mg/kg/day 18SAB075 (i.p.) and of benznidazole (100 mg/kg/day by gavage) given at 5 and 8 dpi was evaluated through parasitemia levels (top) and cumulative mortality (bottom).
