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Activity of arylimidamides (at 1 μg/ml) against intracellular forms of T. cruzi (Tulahuen strain transfected with β-galactosidase) after treatment for 96 h at 37°C
| Compound | Inhibition of the host cell infection (mean ± SD) (%) |
|---|---|
| 16DAP002 | 58 ± 31 |
| 18SAB075 | 50 ± 7 |
| 26SMB070 | 15 ± 8 |
| 16SAB079 | 4 ± 5 |
| 23SMB054 | 3 ± 4 |
| 23SMB022 | 1 ± 1 |
| 27SMB009 | 0 ± 0 |
| 23SMB026 | 0 ± 0 |
| Benznidazole | 82 ± 3 |
