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. 2014 Jul;58(7):3626–3635. doi: 10.1128/AAC.00123-14

TABLE 2.

Overview of FKS mutations found in clinical isolates gained between 2004 (x.04) and 2012 (x.012) from the index/case patient

Isolate FKS1 hot spot 1 mutation by positiona:
FKS1 hot spot 2 mutation by positiona:
1641 (A) 1653 (A) 1662 (T) 1929 (A) 1939 (A) 1946 (C) 4215 (C) 4230 (T)
SCL 1130.04 A/T A/G T/C T A C C/T T/C
952.04 A/T A/G T/C T A C C/T T/C
5104.04 A/T A/G T/C T A C C/T T/C
RRCL 110.12 A/T A/G T/C T A/G C/T C/T T/C
111.12 A/T A/G T/C T A/G C/T C/T T/C
aab P547 T551 I554 T643 R647R/Gc P649P/Ld I1375 A1410
a

Nucleic acid mutation. Boxheads indicate position (wild-type nucleic acid).

b

Regular type, amino acid change: nucleic acid change does not result in a change of amino acid (regular type); bold type, wild-type amino acid/position/heterozygous mutation.

c

Amino acid change, arginine (R) to glycine (G); codon change, AGA to GGA.

d

Amino acid change, proline (P) to leucine (L); codon change, CCU to CUU.