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. 2013 May 1;126(9):2079–2091. doi: 10.1242/jcs.jcs124404

Fig. 6.

Fig. 6.

Re-expression of PTL-1 rescues age-related abnormal neuron morphology and lifespan reduction in the ptl-1(ok621) mutant. ‘PTL-1 Tg’ refers to the PTL-1::V5 transgene, and the terms ‘wild-type’ and ‘ptl-1(ok621)’ following this refer to the genotype at the genomic ptl-1 locus, whether wild-type or ok621 mutant, respectively. (A) Neuron imaging time course of PTL-1 transgenic worms, showing data for anterior touch receptor neurons visualised using the Pmec-4::gfp reporter. (Ai) Control strains together with the PTL-1 Tg; ptl-1(ok621) rescue strain. (Aii) Effect of the PTL-1 Tg alone, compared with wild-type controls. Worms were imaged every second day from day 1 to day 15. Sample sizes are indicated below the graph. The χ2 test for independence was used to analyse differences between genotypes; ns, no significance; *P<0.05. (B) Survival curves for PTL-1 transgenic worms. n = 100 for each strain at the start of the assay. Results of statistical analysis are shown in the table below.